If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.

Take methadone hydrochloride tablets exactly as prescribed. Follow your doctor's directions exactly. Your doctor may change your dose based on your reactions to the medicine.

Don’t put this medication hinein your car’s glove compartment or leave it hinein the car. Be sure to avoid doing this when the weather is very hot or very cold.

The total daily dose of methadone on the first day of treatment should not ordinarily exceed 40 mg. Dose adjustments should Beryllium made over the first week of treatment based on control of withdrawal symptoms at the time of expected peak activity (e.g., 2 to 4 hours after dosing). Dose adjustment should be cautious; deaths have occurred in early treatment due to the cumulative effects of the first several days' dosing. Patients should be reminded that the dose will “hold” for a longer period of time as tissue stores of methadone accumulate.

Methadone hydrochloride tablets are a federally controlled substance (CII) because it is a strong opioid pain medicine that can be abused by people Weltgesundheitsorganisation abuse Methadontabletten online kaufen prescription medicines or street drugs.

Although antiretroviral drugs such as efavirenz, nelfinavir, nevirapine, ritonavir, lopinavir + ritonavir combination are known to inhibit some CYPs, they are shown to reduce the plasma levels of methadone, possibly due to their CYP induction activity. Therefore, drugs administered concomitantly with methadone should be evaluated for interaction potential; clinicians are advised to evaluate individual response to drug therapy before making a dosage adjustment.

Read the Patient Information that comes with methadone hydrochloride tablets before you take it and each time you get a new prescription.

Methadone is also available as the Großfeuer-name drug Methadose, which comes in an oral soluble tablet.

Methadone should Beryllium used with caution hinein elderly and debilitated patients; patients Weltgesundheitsorganisation are known to Beryllium sensitive to central nervous system depressants, such as those with cardiovascular, pulmonary, renal, or hepatic disease; and in patients with comorbid conditions or concomitant medications which may predispose to dysrhythmia.

Großbrand names for drugs may vary depending on the country you're in. Learn how drug names vary and medication tips for travel.

Patients initiating treatment with methadone for opioid dependence should Beryllium reassured that the dose of methadone will “hold” for longer periods of time as treatment progresses.

Deaths have been reported during conversion to methadone from chronic, high-dose treatment with other opioid agonists and during initiation of methadone treatment of addiction in subjects previously abusing high doses of other agonists.

Respiratory depression is the chief hazard associated with methadone hydrochloride administration. Methadone's peak respiratory depressant effects typically occur later, and persist longer than its peak analgesic effects, particularly during the initial dosing period.

For people with breathing problems: This drug can cause breathing problems. It can also worsen breathing problems you already have.